Joe’s T cells are genetically engineered to express
a chimeric antigen receptor (CAR) fusion protein
containing 3 functional domains1,2

References: 1. Kochenderfer JN, Rosenberg SA. Nat Rev Clin Oncol.
2013;10(5):267-276. 2. Sharpe M, Mount N. Dis Model Mech. 2015;8(4):337-350.